In case you are not a gamer, from Urban Dictionary:

A play on video games “non-player character” mixed with a play on The Simulation Hypothesis.

An NPC is seemingly a human that is unable to think objectively.

We exist in a simulated reality and some humans take on the role of NPCs, spouting “opinions” they are programmed to spout and repeating in a cult-like manner.

If, and when, Slow Joe does a live media appearance, he can attempt to refute President Donny’s characterization.